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  • These systems are responsible for control of many automatic functions of the body such as blood pressure, heart rate and digestive processes.There are two types of GPCRs, viz chemosensory (type A, eg rhodopsins)and endo (type B, eg glucagon) GPCRs.Receptor structureGPCRs are integral membrane proteins that possess seven membrane-spanning domains or transmembrane helices (Figure 1).
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