bout to suffer HD. Preferably, the subject is a primate, more preferably a higher primate, most preferably a human. [0125] HD-Nonspecific Oligonucleotide Compositions and Methods for Disaggregation of Huntingtin Aggregations [0126] To our great surprise, we discovered as a byproduct of the targeted gene alteration experiments reported in the Examples below that certain of the control oligonucleoti