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  • st 10 12 M 1 and/or with an affinity less than 500 nM, preferably less than 200 nM, more preferably less than 10 nM, such as less than 500 pM. The affinity of the analog against EGFR or IGF-IR, respectively, can be determined in a manner known per se, for example using the assay described herein.
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