Chemokines such as IL-8 and CCL2 are known to mediate the influx of immune cells in the central nervous system compartment during bacterial meningitis, and CXCL13 is the major determinant of B cell recruitment into the cerebrospinal fluid during neuroinflammation, explained Dr. Philipp. Infection with Bb led to many histopathologic findings in infected animals not treated with dexamethasone, suc