A set of point mutations can be very significant. <a href="http://en.wikipedia.org/wiki/Point_mutationA">http://en.wikipedia.org/wiki/Point_mutationA</a> point mutation, or single base substitution, is a type of mutation that causes the replacement of a single base nucleotide with another nucleotide of the genetic material, DNA or RNA.Here is some on about nucleotides:http://en.wikipedia.org/wiki/NucleotideNucleotides are molecules that, when joined to