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  • Consequently, anomalies consisting notably of vaginal adenocarcinoma and deformations of the uterine cavity (specifically, T-shaped uterus) were identified in the daughters of women who had taken this medication.8 A study carried out on rats exposed intrauterinely to DES reported modifications to Dkk2, Nkd2, sFRP1, hox, Wnt and Eph gene expression.
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