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  • formula XCH2 R, wherein R is a 5-methyl-3-pyridyl group and X represents a halogen atom, such as chlorine or bromine, in the presence of a proton scavenger base such as triethylamine or pyridine in a suitable solvent such as carbon tetrachloride, dichloromethane or chloroform; or alternatively, III is allowed to react with 5-methylnicotinic acid or an equivalent acylating reagent in a manner known
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