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  • n Alzheimer disease (AD) (Olsson et al. 1998; Power et al. 2001; Greco et al. 2008, 2009b).AD is a pathologically complex disease characterized by multiple etiological and biochemical aberrations including oxidative stress, cell cycle aberration, transition metal dyshomeostasis, neurofibrillary tangle (NFT) formation, and amyloid-?? (A??) oligomerization/fibrillation (Castellani et al. 2010).
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