• Corticosteroids have long been used for the management of rheumatoid arthritis and IBD???s diseases, but they suffer from some serious adverse effects, such as Cushing???s habitus, hypertension, hyperglycemia, muscular weakness, increased susceptibility to infection, osteoporosis, glaucoma, psychiatric disturbances, growth arrest, etc.Likewise, the side effects associated with the use of NSAIDs, s