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  • Some PET studies also found decreased metabolism at baseline in medial prefrontal cortex/anterior cingulate.47,59,70,72 Other PET studies in patients with depression and a range of comorbid conditions found decreased metabolism and/or blood flow in the prefrontal cortex, including orbitofrontal cortex and anterior cingulate.73???76 Patients with depression showed a blunted metabolic response to ch
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  • pubmedcentralcanada.ca