| http://www.w3.org/ns/prov#value | - However, several recent studies have shown that multiple hormonal changes occur immediately after removal of the sex organs, and these changes have a significant effect on appetite, metabolism, and other hormones determining metabolic status.3,5-7 The metabolic changes include alterations in levels of leptin, progestins, estrogen, prolactin, insulin-like growth factor (IGF-1), and other hormones.3
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