| http://www.w3.org/ns/prov#value | - Consistent with TOP's broad anatomic and subcellular distribution, it is implicated in hydrolyzing peptide substrates involved in vital functions such as blood pressure control, reproduction, nociception and antigen presentation, [8-13].A distinguishing feature of the X-ray crystallographic-derived structures of the apo- (substrate free) forms of TOP [14] and neurolysin [4] is their catalytic site
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