| http://www.w3.org/ns/prov#value | - Most functions of mTORC1 are inhibited by rapamycin, a triene macrolide antibiotic synthesized by Streptomyces hygroscopicus[28,33]. mTORC1 has to be regarded as a key node in cell signaling because it integrates many intra- and extracellular signals, such as growth factors [insulin, insulin-like growth factor 1 (IGF-1)], energy-sensing signals (glucose, the AMP/ATP-ratio regulating AMPK) and, mos
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