| http://www.w3.org/ns/prov#value | - Interestingly, IL-4, IL-10 and IL-13 that are classified as anti-osteoclastogenic cytokines according to their influence on bone, have fully proven their anti-inflammatory role in OA. They were increased in synovial fluid of OA patients and were shown to inhibit a number of pro-inflammatory cytokines, such as IL-1??, TNF-??, PGE2, etc. (161).
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