| http://www.w3.org/ns/prov#value | - TGF-??1 plays a key role in connective tissue regulating the response of fibroblasts to injury, remodelling, scarring, and pathological production of fibrosis.22 Langevin et al. stated that in cases of minor sprains and repetitive motion injuries, scarring is mostly detrimental since it can contribute to maintaining the chronicity of tissue stiffness, abnormal movement patterns, and pain.
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