| http://www.w3.org/ns/prov#value | - CD40 intracellular signaling is mediated by the recruitment of TNFR-associated factors (TRAFs), which in turn activate different pathways, such as the canonical and noncanonical NF-??B pathway, MAPKs, PI3K and the phospholipase C?? pathway [121].CD40/CD40L pathway is crucial for the development of antitumor immunity.
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