| http://www.w3.org/ns/prov#value | - Physicians have been using TCAs, such as amitriptyline and nortriptyline (Pamelor), to treat neuropathic pain for years, without approved labeling from the U.S. Food and Drug Administration (FDA).8 An updated Cochrane review of antidepressants for treating neuropathic pain revealed an overall effectiveness, with an NNT of 1.3 for diabetic neuropathy based on five studies involving TCAs.8
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