| http://www.w3.org/ns/prov#value | - Subsequently published data found no adverse effects, such as neurotoxicity, and sustained NTN expression up to 12 months after AAV-NTN treatment [87, 88].Following these encouraging animal studies, 12 patients with PD for at least 5 years underwent bilateral stereotactic intraputaminal injections of AAV serotype 2-neurturin (AAV2-NTN) in an open-label phase I study [59].
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