| http://www.w3.org/ns/prov#value | - A tissue-specific regulatory sequence(s) canbe operably linked to the transgene to direct expression of the kinase protein to particular cells.Methods for generating transgenic animals via embryo manipulation and microinjection, particularly animals such as mice, have become conventional in the art and are described, for example, in U.S. Pat. Nos. 4,736,866 and 4,870,009, both byLeder et al., U.S.
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