| http://www.w3.org/ns/prov#value | - By removing an acetyl group of the mitochondrial antioxidant enzyme SOD2, SIRT3 reduces free radical oxidation.30 A major breakthrough occurred when Dr.Verdin???s research team demonstrated that mice lacking SIRT3 show accelerated obesity, insulin resistance, and other symptoms of the metabolic syndrome when fed a high fat diet.31 A high fat diet normally has this effect on mice,32 but the effect
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