| http://www.w3.org/ns/prov#value | - Cyclooxygenase 2 (COX-2), which is primarily responsible for prostaglandins produced at inflammatory sites, is virtually undetectable in most tissues under physiologic conditions but is upregulated in various cancers including head and neck cancers.4,5 To take advantage of this tumor-specific expression, we have recently generated the COX-2 promoter???based replication-selective adenoviral vector,
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