| http://www.w3.org/ns/prov#value | - My group is using transgenic mouse models to study the mechanisms of human neurodegenerative diseases, particularly AD and PD. There are three broad areas of active interest. 1) Understanding the pathogenesis/progression of PD using alpha-synuclein and LRRK2 transgenic mouse models. 2) Mechanisms of amyloid-dependent neurodegeneration using transgenic mouse models of AD. 3) Pathologic interactions
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