| http://www.w3.org/ns/prov#value | - They may also cause damages directly as cytokines such as TNF-a are known to cause increased apoptosis.[7] Drugs are considered to be the commonest cause of TEN. Drug metabolites such as hydroxylamines and arene oxides derived from sulfonamides and aromatic anticonvulsants, respectively, bind to cell constituents if they are not rapidly detoxified by epoxide hydrolase.
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