| http://www.w3.org/ns/prov#value | - It is presumed that several factors including temperature shock, oxidative stress, toxicity of cryoprotectants, cryo-injuries, intracellular ice formation, pressure of vacuum in freeze- and liquid-drying, and formation of free-radicals may induce different kinds of genotypic and phenotypic changes in the cultures (Fleck, 1998; Day et al., 2000; Fleck et al., 2000; Benson & Bremner, 2004).
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