| http://www.w3.org/ns/prov#value | - ApoE, especially apoE4, appears to enhance A?? oligomers.The current view of AD pathophysiology emphasizes the deleterious effects of A?? oigomers on synapses, leading to synaptic dysfunction, and progressive memory impairment in AD patients (Lesn?? et al., 2006; Shankar et al., 2008; Li et al., 2009; Wu et al., 2010).
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