| http://www.w3.org/ns/prov#value | - Failure of Elimination of amyloid-?? (A??) from the brain in Alzheimer's disease.A. In the normal young brain, A?? is produced by neurons and other cells, diffuses through the extracellular spaces and is either degraded by neprilysin and insulin-degrading enzyme (IDE) or absorbed into the blood via lipoprotein receptor-related protein (LRP)-1 mediated mechanisms.
|
