| http://www.w3.org/ns/prov#value | - Additionally, marked reductions in the capacity to produce cytokines, especially IL-2, as well as diminished secondary proliferative responses are hallmarks of inadequately helped memory CD8 T cells [30, 91, 92, 95???97, 99???101].It has been proposed that CD4 T cells operate to ???program??? the development of robust, long-lived memory CD8 T cells [95, 96].
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