| http://www.w3.org/ns/prov#value | - Our observations provide insights into the role of SQSTM1-mediated NF-??B signalling in PDB aetiology, and demonstrate that different mutations in close proximity within loop 2/helix 3 of the SQSTM1 UBA domain exert distinct effects on protein structure and stability, including indirect effects at the UBA/ubiquitin-binding interface.
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