| http://www.w3.org/ns/prov#value | - NF??B plays an important role in mediating inflammatory immune responses and in apoptosis, regulating the expression of several genes, including VEGF and RAGE. VEGF expression increases in retina with the concomitant increase of AGE-RAGE interaction, giving rise to several cellular signaling cascades, including p44, p42, MAPKs and PKCs [29].AGEs may also bind to other receptors, such as the macrop
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