| http://www.w3.org/ns/prov#value | - Traditionally, activation of TLRs in APCs would lead to the production of IFN-??, proinflammatory cytokines such as TNF-??, IL-1 and IL-6, and the cytokines IL-12 and IL-18 that instruct Th1 to differentiate, whereas an increased Th2 response was observed in MyD88 deficient mice with impaired TLRs signaling [282???284].
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