| http://www.w3.org/ns/prov#value | - Alternatively, it is possible that a single PDK2-type enzyme exists but that several phosphatases differentially regulate the AktS473 site.Of the three Akt isoforms (Akt1, Akt2, and Akt3), Akt2 is highly expressed in insulin-responsive tissues such as skeletal muscle, heart, liver, and adipose tissue (7).
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