| http://www.w3.org/ns/prov#value | - The extrinsic pathway is regulated by proteins such as Fas (also called Apo-1 or CD95), and it involves specific caspases, in particular caspase 8, a connecting ligand binding at the cell surface to apoptotic induction [18].Apoptotic dysregulation in varicose veins is shown to be mediated via the intrinsic pathway.
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