| http://www.w3.org/ns/prov#value | - TNF is a potent proinflammatory cytokine secreted by many innate immune cells, particularly activated macrophages, but also neutrophils, mast cells, eosinophils, DCs, and NK cells.31,32,43,71,72 The exocytic pathways responsible for TNF release vary between these cell types, and in macrophages TNF is released by constitutive exocytosis only after being synthesized in response to inflammatory stimu
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