| http://www.w3.org/ns/prov#value | - Signalling through this pathway controls expression and/or activity of many proteins, including ion channels and transcription factors (Toledo-Aral et al. 1995; Minichiello et al. 2002; Klein et al. 2005).In addition to its effects on cytoplasmic signalling pathways, PLC-??1-mediated depletion of PtdIns (4,5)P2 directly affects the activity of membrane proteins that interact with phosphatidylinosi
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