| http://www.w3.org/ns/prov#value | - Given the role of MTHFR in DNA synthesis, it is part of pathways that are acted on by several chemotherapeutic antineoplastic and antirheumatic drugs, such as methotrexate and 5-fluorouracil, although none act directly on the MTHFR protein, reviewed in Innocenti and Ratain, 2002 [Article:11916544] and Maring et al, 2005 [Article:16041392].
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