| http://www.w3.org/ns/prov#value | - of IL-21 in the course of T cell???dependent B cell responses (Crotty, 2011), in autoimmune models such as the BXSB-Yaa and the MRL/lpr mice, one can observe the expansion of extrafollicular T helper cells, which express high levels of ICOS and IL-21 but do not express high-levels of CXCR5 (Odegard et al., 2008; Bubier et al., 2009).
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