| http://www.w3.org/ns/prov#value | - In the hypothalamus, leptin inhibits food intake through mTOR activation, and mTOR inhibition with rapamycin prevents leptin-induced anorexia [58, 59].In a condition of lack of food and consequent reduction of the body fat mass, low levels of leptin lead to a reduced metabolic waste to preserve the energy necessary to support the functions of vital organs such as heart, kidney, and brain; on the o
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