| http://www.w3.org/ns/prov#value | - In addition, DHA is an n-3 PUFA that actsas a competitive substrate for the n-6 PUFA metabolism thatconverts arachidonic acid into inflammatory mediators such asprostaglandins and leukotrienes.22COX-2 is responsible for theoverproduction of PGE2from arachidonic acid during the inflam-matory processes and its expression23and LTB4 production areincreased during IBD. Four-hour incubationwith fish oil
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