| http://www.w3.org/ns/prov#value | - Given these results, here we analyzed the effect of HEXIM1 on the expression of HIF-1?? and VEGF and on myocardial angiogenesis of RV in PH. We revealed that overexpression of HEXIM1 prevented hypoxia-induced expression of HIF-1?? protein and its target genes including VEGF in the cultured cardiac myocytes and fibroblasts, and that cardiomyocyte-specific HEXIM1 transgenic mice repressed RV myocard
|
