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  • Another interesting thing is the in vivo half-time, although artesunate has the shortest half-time (10 mins oral), which implies it should not stay long in the body especially in brain, but one trial shows that with one intravenous of artesunate, they measured accumulation of DHA in CSF. This should explain why artesunate can be used to cure cerebral malaria??? And, artesunate's half-time is 10 mi
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