| http://www.w3.org/ns/prov#value | - In osteosarcoma SDC2 has been shown to induce apoptosis.42,43 We excluded mutations in the nuclear localization signal, located at the first exon of the SDC2 gene, however other mechanisms such as aberrant phosphorylation of the nuclear localization signal or mutations in a kinase responsible for the phosphorylation of the nuclear localization signal might explain the aberrant localization of SDC2
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