| http://www.w3.org/ns/prov#value | - In FH patients, low HDL-C levels have been shown to be an independent risk factor to the development of CVD. HDL-C levels are affected by risk factors such as sex, obesity, smoking, diet, alcohol consumption, and exercise, as well as genetic polymorphisms leading to variations of HDL-C levels in FH patients.112 A Phase III study of anacetrapib is currently underway in a large cohort of heFH patien
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