| http://www.w3.org/ns/prov#value | - Once these new blood vessels become embedded in the tumor, they provide a means for tumor cells to enter the circulation and metastasize to distant sites such as liver, lung or bone (Weidner, N., et al., The New England Journal of Medicine, 324(1): 1-8 (1991)). [0005] To date, several naturally occurring angiogenic factors have been described and characterized (Fidler, J. I. and Ellis, L. M., Cell
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