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  • In the current study, PTIO treatment attenuated MMP loss and decreased caspase activation (Figure 3A???C), suggesting that NO generation is an important mediator of apoptosis in PDT-exposed HUVECs.Recently, our laboratory and other researchers showed that PAK2 is a target substrate for caspases activated by various apoptotic stimuli, including anti-Fas antibodies, tumor necrosis factor-??, ceramid
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  • mdpi.com