| http://www.w3.org/ns/prov#value | - In prior studies, medications such as NMDA antagonists, GABA agonists, and opioids have all been shown to produce analgesic benefits and reduce temporal summation of pain (49???53); future studies may benefit from examination of potential abnormalities in these neurotransmitter systems in RLS patients.The fact that pain thresholds were reduced in RLS patients at multiple anatomic locations suggest
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