| http://www.w3.org/ns/prov#value | - Cancer cells contain many common aberrations in the machinery that regulates apoptosis, including increased activity of antiapoptotic proteins, such as Bcl-2 and Mcl-1, or increased levels of inhibitors of apoptosis, such as the protein survivin, which inhibits caspase activity.Epigenetic changes in gene expression are also hallmarks of malignancy (Chapter 186).
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