| http://www.w3.org/ns/prov#value | - Similarly, physiological barrier-stabilizing mediators and signalling pathways such as cAMP apparently activate Rac1 together with Cdc42, presumably via the GEF Vav2.28,36,37 Moreover, because the barrier-stabilizing effect of oxidized phospholipids (OxPAPCs) was blocked by siRNA targeting Cdc4238 and expression of constitutively active Cdc42 blunted LPS-induced lung vascular permeability in vivo,
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