| http://www.w3.org/ns/prov#value | - CD40 engagement in both T or B cells leads to the production of cytokines, such as IL-12, IL-2, TNF-??, IFN-??, and CD80, developing an environment which is conducive to autoimmune diseases [172???174].Additionally, the interaction between CD40 and CD40L regulated by NF-??B can regulate the expression of numerous biomolecules in other cells.
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