| http://www.w3.org/ns/prov#value | - Transcription of MMPs is regulated either positively or negatively by various effectors, including growth factors and cytokines, such as interleukins (IL-1, IL-4 and IL-6), chemokines, transforming growth factors (EGF, HGF and TGF??) or tumor necrosis factor alpha (TNF??) and other factors [35,50,76,80,81,82,83].Post-translational modifications, such as activation of pro-MMP precursor zymogens and
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