| http://www.w3.org/ns/prov#value | - Previous studies have shown that host-pathogen interactions modulate the severity of GAS sepsis [5],[6],[9],[10], and we found that patients with GAS sepsis expressing HLA class II DRB1*15/DQB1*06 (DR15/DQ6) haplotype are protected from severe GAS sepsis, whereas those with HLA class II DRB1*14/DQB1*05 (DR14/DQ5) haplotype are at high risk for developing severe and often fatal forms of the disease
|
